Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle Pathogenesis
نویسندگان
چکیده
منابع مشابه
Activation of JNK1 contributes to dystrophic muscle pathogenesis
Duchenne Muscular Dystrophy (DMD) originates from deleterious mutations in the dystrophin gene, with a complete loss of the protein product. Subsequently, the disease is manifested in severe striated muscle wasting and death in early adulthood. Dystrophin provides a structural base for the assembly of an integral membrane protein complex. As such, dystrophin deficiency leads to an altered mecha...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2012
ISSN: 1525-0016
DOI: 10.1038/mt.2012.35